ABSTRACT
Introduction: Fine needle aspiration cytology (=FNAC) is most popular diagnostic aid in patients with lymphadenopathy. This paper proves it to be highly sensitive also. Materials and Methods: The study comprises 300 lymph node aspirates done at Shri Mahant Indiresh Hospital of SGRR Medical College during a period of two years from January 2009 to December 2010. Results: Cytology was unsatisfactory in 3.3% (n=3) cases; showed reactive non specific lymphadenitis in 41.7% (n=125) cases; tuberculosis in 31.7% (n=95) cases; primary lymphomas in 6.3% (n=19) cases and metastatic tumor in 10.7% (n=32) cases. Conclusion: FNAC is a very sensitive procedure in patients with lymphadenopathy; sensitivity of 96.7% reported in our study.
Subject(s)
Age Groups , Biopsy, Fine-Needle/methods , Female , Humans , India , Lymph Nodes/cytology , Lymph Nodes/diagnosis , Lymphatic Diseases/cytology , Lymphatic Diseases/diagnosis , Lymphadenitis/cytology , Lymphadenitis/diagnosis , Lymphoma/cytology , Lymphoma/diagnosis , MaleABSTRACT
Introduction: Imprint cytology is proved to be rapid inexpensive tool in the diagnosis of various lymph node lesions. Objective: The present study was conducted to correlate the diagnostic accuracy, sensitivity and specificity of imprint cytology of various lymph node lesions with histopathological diagnosis. 102 cases were included in the study comprising inflammatory lesion, tubercular lymphadenitis, lymphomas and metastatic carcinomas. Material and Method: From 102 cases of lymph node excision, imprint smears were taken and stained with Hematoxylin & Eosin and Papanicolaou stains. The findings of imprint cytology were then compared with final histopathological diagnosis. Result: When compared with final histopathological diagnosis, imprint smears showed overall diagnostic accuracy of 97.8% with sensitivity and specificity of 95.05% and 98.69% respectively. Accuracy rate for metastatic lymphadenopathy was 100%, whereas, for tubercular lymphadenitis it was 98.04% and for lymphomas 96.04%. Conclusion: Imprint cytology proved to be very useful for diagnosis of metastatic tumour as it gave 100% diagnostic accuracy, sensitivity and specificity. Imprint cytology is also considered to be useful in superficial ulcers to differentiate between benign and malignant lesions without surgical intervention.